EPIDEMIOLOGY OF MAJOR LOWER LIMB AMPUTATION USING ROUTINELY COLLECTED ELECTRONIC HEALTH DATA IN THE UK: A SYSTEMATIC REVIEW PROTOCOL

Epidemiology of major lower limb amputation using routinely collected electronic health data in the UK: a systematic review protocol

Introduction It is estimated that peripheral arterial disease occurs in one in five people aged over 60 years in the UK.Major lower limb amputation is a debilitating and life-changing potential outcome of peripheral arterial disease.A number of risk factors are involved in the development of the disease including smoking and diabetes.There is debat

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Outpatient management of severe early OHSS by administration of GnRH antagonist in the luteal phase: an observational cohort study

Abstract Background Management of established severe OHSS requires prolonged hospitalization, occasionally in intensive care units, accompanied by multiple ascites punctures, correction of intravascular fluid volume and electrolyte imbalance.The aim of the present study was to evaluate whether it is feasible to manage women with severe OHSS as outp

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Practice, Constraint, and Mathematical Concepts

In this piece I articulate and defend a conception of mathematical practice and mathematical subject-matter, which is responsive both to a sensible pluralism concerning the connection between inferential practices and guiding interests, on the one hand, and to the objective content-determining structure of mathematical concepts on the other.I begin

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